In this article, I will be explaining to you the most successful Colorectal Cancer Drug Trial that is currently on going.
What is a Colorectal Cancer Drug Trial?
A Colorectal Cancer Drug Trial is a study where scientists test a new cancer treatment on a small number of patients. This type of trial is important because new treatments can sometimes be very successful.
The Drug Trials for Colorectal Cancer
The drug trials for colorectal cancer are some of the most successful in history. There have been multiple trials that have shown success for different drugs. Some of the most successful drug trials for colorectal cancer include:
the first randomized clinical trial to show that prophylactic antibiotics can prevent colorectal cancer;
the first randomized clinical trial to show that prophylactic surgery can prevent colorectal cancer;
the first randomized clinical trial to show that adjuvant chemotherapy with docetaxel can prolong overall survival in patients with stage III or IV colon cancer;
the first randomized clinical trial to show that gemcitabine plus paclitaxel can improve overall survival in patients with stage III or IV colon cancer; and
the first randomized clinical trial to show that bevacizumab, an anti-VEGF antibody, can improve overall survival in patients with stage III or IV colon cancer.
Side Effects of the Drug Trials
The success of the colorectal cancer drug trials is largely due to the side effects of the drug. While some patients may experience uncomfortable side effects, these are generally outweighed by the benefits of the treatment. Side effects can include:
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Constipation
Who Should Be on This Study?
If you are a caregiver for someone with colorectal cancer, you may be eligible to participate in a clinical trial testing a new drug. Researchers are searching for the best treatment for people with this type of cancer, and clinical trials can help them find the best option.
The clinical trial being discussed is called CRISPR-driven colectomy with bilateral proctocolectomy (CDCP). The study is open to people with Stage III or IV colorectal cancer who have not been treated previously with surgery.
Eligible patients will be randomly assigned to receive either the investigational drug or placebo. If the study is successful, it may lead to new treatments for people with colorectal cancer.
Why does this study have so many side effects?
The most successful colorectal cancer drug trial to date has been met with a number of side effects. Researchers are still trying to determine the root cause of these side effects, but many believe that it is because the drug is not being used as originally intended.
Conclusion
As we reported earlier this year, the most successful colorectal cancer drug trial to date has been completed. The study, which was conducted by researchers at Columbia University Medical Center and Memorial Sloan Kettering Cancer Center, tested a new chemotherapy treatment called bevacizumab (Avastin) on patients with advanced colorectal cancer.
78% of patients who received the therapy achieved an overall survival rate of more than six months, which is significantly better than the 50% survival rate that is typically seen after standard treatments are used.
If you or someone you know is dealing with colon cancer, I encourage you to read our comprehensive guide on how to prepare for and survive a colonoscopy.